APRIL-OCELOT

Azithromycin for Preventing the development of upper Respiratory track Illness into Lower respiratory track symptoms in children (APRIL), and Oral Corticosticosteroids for treating Episodes of significant LOwer respiratory Tract symptoms in children (OCELOT)

APRIL and OCELOT are two separate but linked studies of pre-school age children with asthma. They are designed to identify new treatment approaches to recurrent, severe episodes of lower respiratory tract symptoms in these young children. This combined study is currently recruiting children between 12 and 71 months of age in the following locations:

Albuquerque, NM Atlanta, GA Boston, MA Charlottesville, VA Chicago, IL Cleveland, OH Denver, CO Madison, WI Milwaukee, WI Oakland, CA Pittsburgh, PA Raleigh, NC St. Louis, MO San Francisco, CA Tucson, AZ Winston-Salem, NC

For more information, click on the location near you above. The enrollment goal for APRIL/OCELOT is 600 participants.

INFANT-AVICA

INdividualized therapy For Asthma iN Toddlers (INFANT), and Acetaminophen Vs. Ibuprofen in Children with Asthma (AVICA)

INFANT and AVICA are two separate but combined studies. INFANT is designed to determine whether one asthma controller-medication for preschool children with persistent asthma works better than another for these children, and to see if there is something about a child that helps doctors predict which treatment would work better. For example, maybe one treatment works best in boys who also have allergies. AVICA is designed to find out if different fever/pain medicines have an effect on asthma symptoms in preschool children with persistent asthma. This combined study is currently recruiting children between 12 and 59 months of age.

Atlanta, GA Boston, MA Charlottesville, VA Chicago, IL Cleveland, OH Denver, CO Madison, WI Oakland, CA Pittsburgh, PA St. Louis, MO San Francisco, CA Tucson, AZ Winston-Salem, NC

For more information, click on the location near you above. The enrollment goal for INFANT-AVICA is 294 participants.